Please not that I am not a doctor in medicine but a concerned citizen who takes prof. Testart’s warning on the necessary role of citizens seriously.
Here is the article : « Coronavirus Uses Same Strategy As HIV To Evade, Cripple Immune System: Chinese Study Finds », by Tyler Durden, Tue, 05/26/2020 – 21:46 https://www.zerohedge.com/health/coronavirus-uses-same-strategy-hiv-evade-immune-response-chinese-study-finds
The article underlines the role of undeniable « HIV insertions » in the SARS-CoV-2 viruses. According to a Chinese study, provided in this article, these insertions affect the immune system. If such were the case, herd immunity would be impossible to achieve and the search for a vaccine will turn out to be as difficult as it has proven to be for HIV.
Therefore, the best strategy seems to be the preventive suffocation of the spreading of the Covid-19. Based on what I have read on the subject, I am personally convinced that massif oral and nasal testing should be performed in tandem with the early administration of prof. Raoult’s Protocol. This does in no way detract from other cures if and when patients need to be hospitalized, but as the actual developments do show in Marseille, it will make hospitalization less likely and strongly prevent death from Covid-19. Reality show that, although it was not propagandized, lethality form Covid-19 in red zones started to tend downwards when doctors finally decided to act as doctors and began to prescribe prof. Raoult treatment, in absence of other good alternatives.
As we know, thanks to his carefully devised Protocol involving the administration of Hydroxychloroquine with the antibiotic Azithromycine immediately after detection of the illness, prof. Raoult has managed to obtain a 0.5 % rate of lethality from Convid-19 – not to be confused with the generic rate of mortality given by x dead over 1 million. This compares with a lethality rate hovering around 14 % in Italy and in other countries. It is impressive. (see details here : http://rivincitasociale.altervista.org/covid-19-loffensive-criminelle-philo-semite-nietzscheenne-contre-la-science-et-la-sante-des-citoyens-24-mai-2020/ )
This is what one can read in the Chinese study : « Furthermore, the specific autophagy inhibitors chloroquine (CQ) and E64/pep restored the expression of MHC-I both on cell surface and total protein level (Fig. 3DS3E), ». (1) Such a statement, as well as earlier studies concerning the preventive role of zinc, cannot be ruled out. Science must predominate, not Big Pharma’s narratives, especially within governmental instances and the WHO.
If indeed the SARS-CoV-2 cripples the immune system, then the preventive suffocation of the spreading of Covid-19 should be the World priority. Total regional – or national – confinement will help lower the peak which otherwise would be expected given the relatively high R0 exponential spreading function of theSARS-CoV-2. Once this is achieved however, confinement can become selectively targeted if and only if – in my understanding – massive oral and nasal testing are performed together with the administration of the Protocol of prof. Raoult. Massive testing will naturally allow non authoritarian tracing of the contacts of the infected person by the front-line medical personnel and lead to selective quarantine. Venal electronic control freaks and their MIT’s tracing tattoos are not needed and, in any case, will not prove efficient from the health-care point of view. But such dangerous social control drifting can quickly become a grievous peril for our basic fundamental rights, in particular the control over our personal data.
Prof. Raoult has mentioned sequels that show up even in asymptomatic patients. If this is proven, it will have the potential to aggravate the general epidemiological picture in given societies, especially those with an older demographics, at a time when the dismantling of public health-care systems causes millions to renounce or postpone health-care. (more than 11 million in France and Italy, for instance, not exactly what one would consider poor countries …)
The massive testing militated for the rehabilitation of the public health-care system, complete with the front-lines structures and the development of a public Pharmacare. And as prof. Raoult, a acknowledged expert in his disciplines, proposes the rehabilitation of know molecules. ( see : http://rivincitasociale.altervista.org/health-care-between-cuts-and-corruption-victim-of-choice-for-neoliberal-and-monetarist-fiscal-federalism-may-2016-translated-april-6-2020/) While the combination Hydroxychloroquine-Azithromycin does cost only a few dollars, other unproven and apparently toxic drugs would cost vastly more around a few hundred dollars for the lowest estimate. This is apparently the case for remdesivir, which is not yet on the market, but feverishly quoted in the Stock exchange. (2) We know that Big Pharma representatives do their selling jobs with doctors and hospitals often turning those in so many drug pushers for their products. Governmental directives should put order into this dangerous and messy situation. Health-care must remain the precincts of life-saving consideration rigorously following the Hippocratic Oath, not a merchant business.
Prof Raoult has underlined the seasonal aspect of these kind of viruses. Prof Montagnier has said that Nature has a tendency to eliminate such chimeras. I certainly hope that both turn out to be right despite what comes out of this new important Chinese study. The question needs further scientific investigation. Meanwhile I would personally hope for major countries, for instance China, to give the opportunity to prof. Montagnier to quickly conduct his experiments which has nothing to do with a folkloristic « water memory » but instead with the most advanced concepts in physics-chemistry. (see https://www.youtube.com/watch?v=feKMcr–tM0 ) If prof Montagnier turns out to be right if would be a major development in the Human History.
Independently of the fact that SARS-CoV-2 was artificially modified – which is my personal informed opinion given that the natural insertion of HIV specific chains are statistically unlikely – or not, the point is that civilian high security labs are necessary with stringent protocols and security measures in order to develop and provide preventive methodology and therapies. However, these laboratories should come under a new and reinforced set of arms control treaties for bio-weapons, chemical weapons and for highly destabilizing intermediate nuclear weapons.
The blaming game has no healthy benefits for anyone. The Fort Detrick Maryland, epidemics of flu with strange pneumonia symptoms killing over 10 000 Americans in July-August 2019, should be duly investigated.
Paul De Marco
Notes:
1 ) Here are two quotes from the Chinese study : « The ORF8 Protein of SARS-CoV-2 Mediates Immune Evasion through Potently Downregulating MHC-I ,
A ) « Furthermore, the specific autophagy inhibitors chloroquine (CQ) and E64/pep restored the expression of MHC-I both on cell surface and total protein level (Fig. 3DS3E), »
(…)
B ) Discussion
Viral infection would elicit effective innate and adoptive immune response to inhibit the viral replication. Apparently, the anti-viral immunity on SARS-CoV-2 infection remains largely unknown. A proportion of recovered patients still exhibit as the virus carriers and the case of CD8+ lymphocytes dysfunction was reported.9-12. These clinical characters of COVID-19 suggest that SARS-Cov2 could lead to adoptive immune disorder while remain active viral replication. In this report, we have demonstrated that SARS-CoV-2 ORF8 mediates MHC-I downregulation, which is not observed in any other strains of SARS-CoV. The discrepancy of ORF8 between SARS-CoV-2 and SARS-CoV could at least partially be responsible for specific COVID-19 clinical and pathological characteristics, which somehow behaves as a chronic viral infection. Although some other viruses have also developed the capability to evade the immune surveillance by impairing the antigen presentation, the underlying mechanism is different from each other. HIV-1 Nef mainly facilitates the interaction between AP-1 and MHC and prevent the MHC-I molecule move to plasma membrane.
2 ) « It’s not clear exactly how much the drug will cost. For context, one non-profit that evaluates drug costs says it costs about $9.32 to manufacture a 10-day course of remdesivir treatment for one patient. Calculating the cost of development and trials, the Institute for Clinical and Economic Review says Gilead could charge as little as $390 for the drug. But Wall Street analysts are on an entirely different page, suggesting a price between $5,000 to $10,000, leading to billions in profits.», https://www.politico.com/news/2020/05/06/remdesivir-helps-coronavirus-patients-but-at-what-cost-240230